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Search Results for " sterol 14-alpha demethylase "

Targets

5

Compounds

1

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T0120 Voriconazole UK-109496 Antifection , Antifungal
Voriconazole (UK-109496) is a triazole antifungal agent that specifically inhibits STEROL 14-ALPHA-DEMETHYLASE and CYTOCHROME P-450 CYP3A.
T23174 Posaconazole hydrate Others
Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity. Posaconazole is a sterol C14ɑ demethylase inhibitor (IC50: 0.25 nM). Posaconazole strongly inhibits 14-alpha demethylase, a...
T15708 Lanoconazole Antifungal
Lanoconazole is an orally active imidazole antifungal agent that displays a broad spectrum of activity against fungi in vitro and in vivo. Lanoconazole interferes with ergosterol biosynthesis by inhibiting sterol 14-alph...
TMIH-0604 Voriconazole-d3
Voriconazole-d3 is a deuterated compound of Voriconazole. Voriconazole has a CAS number of 137234-62-9. Voriconazole is a triazole antifungal agent that specifically inhibits STEROL 14-ALPHA-DEMETHYLASE and CYTOCHROME P-...
T60853 (Z)-Lanoconazole
(Z)-Lanoconazole is the Z configuration of Lanoconazole which used for dermatophytosis and onychomycosis investigation. Lanoconazole inhibits sterol 14-alpha demethylase and blocks fungal membrane ergosterol biosynthesis...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPH-03017 CYP51 Protein, Mycobacterium tuberculosis, Recombinant (His & Myc) Mycobacterium tuberculosis Baculovirus Insect Cells
Its precise biological substrate is not known. Catalyzes C14-demethylation of lanosterol, 24,25-dihydrolanosterol and obtusifoliol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'-dimethy...
TargetMol